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Processivity Clamp gp45 and ssDNA-Binding-Protein gp32 Modulate the Fidelity of Bacteriophage RB69 DNA Polymerase in a Sequence-Specific Manner, Sometimes Enhancing and Sometimes Compromising Accuracy

Numerous studies of the impact of accessory proteins upon the fidelity of DNA synthesis have provided a complex and sometimes discordant picture. We previously described such an analysis conducted in vitro using various bacteriophage RB69 gp43 mutator DNA polymerases with or without the accessory pr...

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Detalhes bibliográficos
Main Authors: Bebenek, Anna, Carver, Geraldine T., Kadyrov, Farid A., Kissling, Grace E., Drake, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449605/
https://ncbi.nlm.nih.gov/pubmed/15695359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.037630
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