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Oligosyndactylism Mice Have an Inversion of Chromosome 8

The radiation-induced mutation Oligosyndactylism (Os) is associated with limb and kidney defects in heterozygotes and with mitotic arrest and embryonic lethality in homozygotes. We reported that the cell cycle block in Os and in the 94-A/K transgene-induced mutations is due to disruption of the Anap...

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Autori principali: Wise, Thomas L., Pravtcheva, Dimitrina D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448711/
https://ncbi.nlm.nih.gov/pubmed/15611179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031914
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