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Oligosyndactylism Mice Have an Inversion of Chromosome 8

The radiation-induced mutation Oligosyndactylism (Os) is associated with limb and kidney defects in heterozygotes and with mitotic arrest and embryonic lethality in homozygotes. We reported that the cell cycle block in Os and in the 94-A/K transgene-induced mutations is due to disruption of the Anap...

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Главные авторы: Wise, Thomas L., Pravtcheva, Dimitrina D.
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448711/
https://ncbi.nlm.nih.gov/pubmed/15611179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.031914
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