LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium tuberculosis in human cells

BACKGROUND: Co-infections of human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (M. Tb) are steadily increasing and represent a major health crisis in many developing countries. Both pathogens individually stimulate tumor necrosis factor-alpha (TNF) release from infected cells and TNF...

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Bibliografiska uppgifter
Huvudupphovsmän: Haraguchi, Soichi, Day, Noorbibi K, Kamchaisatian, Wasu, Beigier-Pompadre, Macarena, Stenger, Steffen, Tangsinmankong, Nutthapong, Sleasman, John W, Pizzo, Salvatore V, Cianciolo, George J
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2006
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448187/
https://ncbi.nlm.nih.gov/pubmed/16573838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-6405-3-8
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