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Anti-TNF immunotherapy reduces CD8(+) T cell–mediated antimicrobial activity against Mycobacterium tuberculosis in humans
The incidence of tuberculosis is increased during treatment of autoimmune diseases with anti-TNF antibodies. This is a significant clinical complication, but also provides a unique model to study immune mechanisms in human tuberculosis. Given the key role for cell-mediated immunity in host defense a...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Clinical Investigation
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673881/ https://ncbi.nlm.nih.gov/pubmed/19381021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38482 |
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