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The H1 histamine receptor regulates allergic lung responses
Histamine, signaling via the type 1 receptor (H1R), has been shown to suppress Th2 cytokine production by in vitro cultured T cells. We examined the role of H1R in allergic inflammation in vivo using a murine asthma model. Allergen-stimulated splenic T cells from sensitized H1R(–/–) mice exhibited e...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1448167/ https://ncbi.nlm.nih.gov/pubmed/16680192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26150 |
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