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The H1 histamine receptor regulates allergic lung responses

Histamine, signaling via the type 1 receptor (H1R), has been shown to suppress Th2 cytokine production by in vitro cultured T cells. We examined the role of H1R in allergic inflammation in vivo using a murine asthma model. Allergen-stimulated splenic T cells from sensitized H1R(–/–) mice exhibited e...

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Detalhes bibliográficos
Main Authors: Bryce, Paul J., Mathias, Clinton B., Harrison, Krista L., Watanabe, Takeshi, Geha, Raif S., Oettgen, Hans C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448167/
https://ncbi.nlm.nih.gov/pubmed/16680192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI26150
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