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Population Genetics of Polymorphism and Divergence for Diploid Selection Models With Arbitrary Dominance

We develop a Poisson random-field model of polymorphism and divergence that allows arbitrary dominance relations in a diploid context. This model provides a maximum-likelihood framework for estimating both selection and dominance parameters of new mutations using information on the frequency spectru...

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Detalhes bibliográficos
Main Authors: Williamson, Scott, Fledel-Alon, Adi, Bustamante, Carlos D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448126/
https://ncbi.nlm.nih.gov/pubmed/15454557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.024745
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