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Simultaneous inference of selection and population growth from patterns of variation in the human genome

Natural selection and demographic forces can have similar effects on patterns of DNA polymorphism. Therefore, to infer selection from samples of DNA sequences, one must simultaneously account for demographic effects. Here we take a model-based approach to this problem by developing predictions for p...

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Detalhes bibliográficos
Main Authors: Williamson, Scott H., Hernandez, Ryan, Fledel-Alon, Adi, Zhu, Lan, Nielsen, Rasmus, Bustamante, Carlos D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142382/
https://ncbi.nlm.nih.gov/pubmed/15905331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502300102
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