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Estimating the Degree of Saturation in Mutant Screens

Large-scale screens for loss-of-function mutants have played a significant role in recent advances in developmental biology and other fields. In such mutant screens, it is desirable to estimate the degree of “saturation” of the screen (i.e., what fraction of the possible target genes has been identi...

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Autori principali: Pollock, David D., Larkin, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448089/
https://ncbi.nlm.nih.gov/pubmed/15454559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.024430
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