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Estimating the Degree of Saturation in Mutant Screens

Large-scale screens for loss-of-function mutants have played a significant role in recent advances in developmental biology and other fields. In such mutant screens, it is desirable to estimate the degree of “saturation” of the screen (i.e., what fraction of the possible target genes has been identi...

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Detalhes bibliográficos
Main Authors: Pollock, David D., Larkin, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1448089/
https://ncbi.nlm.nih.gov/pubmed/15454559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.103.024430
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