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The novel SAM domain protein Aveugle is required for Raf activation in the Drosophila EGF receptor signaling pathway

Activation of the Raf kinase by GTP-bound Ras is a poorly understood step in receptor tyrosine kinase signaling pathways. One such pathway, the epidermal growth factor receptor (EGFR) pathway, is critical for cell differentiation, survival, and cell cycle regulation in many systems, including the Dr...

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Autors principals: Roignant, Jean-Yves, Hamel, Sophie, Janody, Florence, Treisman, Jessica E.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447592/
https://ncbi.nlm.nih.gov/pubmed/16600911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1390506
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