Essential Dosage-Dependent Functions of the Transcription Factor Yin Yang 1 in Late Embryonic Development and Cell Cycle Progression

Constitutive ablation of the Yin Yang 1 (YY1) transcription factor in mice results in peri-implantation lethality. In this study, we used homologous recombination to generate knockout mice carrying yy1 alleles expressing various amounts of YY1. Phenotypic analysis of yy1 mutant embryos expressing ∼7...

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Autors principals: Affar, El Bachir, Gay, Frédérique, Shi, Yujiang, Liu, Huifei, Huarte, Maite, Wu, Su, Collins, Tucker, Li, En, Shi, Yang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447422/
https://ncbi.nlm.nih.gov/pubmed/16611997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3565-3581.2006
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