Rad18 Regulates DNA Polymerase κ and Is Required for Recovery from S-Phase Checkpoint-Mediated Arrest

We have investigated mechanisms that recruit the translesion synthesis (TLS) DNA polymerase Polκ to stalled replication forks. The DNA polymerase processivity factor PCNA is monoubiquitinated and interacts with Polκ in cells treated with the bulky adduct-forming genotoxin benzo[a]pyrene dihydrodiol...

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Bibliographic Details
Main Authors: Bi, Xiaohui, Barkley, Laura R., Slater, Damien M., Tateishi, Satoshi, Yamaizumi, Masaru, Ohmori, Haruo, Vaziri, Cyrus
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447421/
https://ncbi.nlm.nih.gov/pubmed/16611994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3527-3540.2006
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