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Rad18 Regulates DNA Polymerase κ and Is Required for Recovery from S-Phase Checkpoint-Mediated Arrest

We have investigated mechanisms that recruit the translesion synthesis (TLS) DNA polymerase Polκ to stalled replication forks. The DNA polymerase processivity factor PCNA is monoubiquitinated and interacts with Polκ in cells treated with the bulky adduct-forming genotoxin benzo[a]pyrene dihydrodiol...

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Bibliografski detalji
Glavni autori: Bi, Xiaohui, Barkley, Laura R., Slater, Damien M., Tateishi, Satoshi, Yamaizumi, Masaru, Ohmori, Haruo, Vaziri, Cyrus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447421/
https://ncbi.nlm.nih.gov/pubmed/16611994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3527-3540.2006
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