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The Retinoblastoma Protein Regulates Pericentric Heterochromatin

The retinoblastoma protein (pRb) has been proposed to regulate cell cycle progression in part through its ability to interact with enzymes that modify histone tails and create a repressed chromatin structure. We created a mutation in the murine Rb1 gene that disrupted pRb's ability to interact...

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Detaylı Bibliyografya
Asıl Yazarlar: Isaac, Christian E., Francis, Sarah M., Martens, Alison L., Julian, Lisa M., Seifried, Laurie A., Erdmann, Natalie, Binné, Ulrich K., Harrington, Lea, Sicinski, Piotr, Bérubé, Nathalie G., Dyson, Nicholas J., Dick, Frederick A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447412/
https://ncbi.nlm.nih.gov/pubmed/16612004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3659-3671.2006
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