The Retinoblastoma Protein Regulates Pericentric Heterochromatin

The retinoblastoma protein (pRb) has been proposed to regulate cell cycle progression in part through its ability to interact with enzymes that modify histone tails and create a repressed chromatin structure. We created a mutation in the murine Rb1 gene that disrupted pRb's ability to interact...

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Huvudupphovsmän: Isaac, Christian E., Francis, Sarah M., Martens, Alison L., Julian, Lisa M., Seifried, Laurie A., Erdmann, Natalie, Binné, Ulrich K., Harrington, Lea, Sicinski, Piotr, Bérubé, Nathalie G., Dyson, Nicholas J., Dick, Frederick A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1447412/
https://ncbi.nlm.nih.gov/pubmed/16612004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.9.3659-3671.2006
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