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Upregulated Transcription of Plasmid and Chromosomal Ribulose Monophosphate Pathway Genes Is Critical for Methanol Assimilation Rate and Methanol Tolerance in the Methylotrophic Bacterium Bacillus methanolicus

The natural plasmid pBM19 carries the key mdh gene needed for the oxidation of methanol into formaldehyde by Bacillus methanolicus. Five more genes, glpX, fba, tkt, pfk, and rpe, with deduced roles in the cell primary metabolism, are also located on this plasmid. By using real-time PCR, we show that...

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Autors principals: Jakobsen, Øyvind M., Benichou, Aline, Flickinger, Michael C., Valla, Svein, Ellingsen, Trond E., Brautaset, Trygve
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446977/
https://ncbi.nlm.nih.gov/pubmed/16585766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.8.3063-3072.2006
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