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Nucleocytoplasmic Shuttling of Pak5 Regulates Its Antiapoptotic Properties

p21-activated kinase 5 (Pak5) is an effector for the small GTPase Cdc42, known to activate cell survival signaling pathways. Previously, we have shown that Pak5 localizes primarily to mitochondria. To study the relationship between Pak5 localization and its effects on apoptosis, we identified three...

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Bibliografiske detaljer
Main Authors: Cotteret, Sophie, Chernoff, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446938/
https://ncbi.nlm.nih.gov/pubmed/16581795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.8.3215-3230.2006
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