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Factors Controlling Fibroblast Growth Factor Receptor-1's Cytoplasmic Trafficking and Its Regulation as Revealed by FRAP Analysis

Biochemical and microscopic studies have indicated that FGFR1 is a transmembrane and soluble protein present in the cytosol and nucleus. How FGFR1 enters the cytosol and subsequently the nucleus to control cell development and associated gene activities has become a compelling question. Analyses of...

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Autores principales: Dunham-Ems, Star M., Pudavar, Haridas E., Myers, Jason M., Maher, Pamela A., Prasad, Paras N., Stachowiak, Michal K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1446089/
https://ncbi.nlm.nih.gov/pubmed/16481405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-08-0749
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