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Fibroblast Growth Factor Receptor-1 (FGFR1) Nuclear Dynamics Reveal a Novel Mechanism in Transcription Control

Nuclear FGFR1 acts as a developmental gene regulator in cooperation with FGF-2, RSK1, and CREB-binding protein (CBP). FRAP analysis revealed three nuclear FGFR1 populations: i) a fast mobile, ii) a slower mobile population reflecting chromatin-bound FGFR1, and iii) an immobile FGFR1 population assoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dunham-Ems, Star M., Lee, Yu-Wei, Stachowiak, Ewa K., Pudavar, Haridas, Claus, Peter, Prasad, Paras N., Stachowiak, Michal K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2675620/
https://ncbi.nlm.nih.gov/pubmed/19261810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0600
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