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Can B-cell tolerance be induced by oligovalent thymus dependent antigens?

Spleen cells from adult mice were rendered "tolerant" to TNP by exposing cells in vitro to large concentrations of TNP10BSA. After such treatment the residual response to TNP was measured using TNP-LPS as antigen in vitro or in vivo. The "tolerance" observed in this system was no...

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Bibliografiske detaljer
Main Authors: Waldmann, H, Pope, H
Format: Artigo
Sprog:Inglês
Udgivet: 1977
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1445321/
https://ncbi.nlm.nih.gov/pubmed/301114
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