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Induction of immunological tolerance requires that the B cells can respond to the polyclonal B-cell-activating properties of the thymus- independent antigens
Mice were rendered specifically tolerant to the fluorescein isothiocyanatedextran (FITC) epitope by injection of FITC-dextran B512. Their spleen cells were removed at various times and cultivated in vitro with different polyclonal B-cell activators, such as lipopolysaccharide (LPS), purified protein...
Tallennettuna:
| Aineistotyyppi: | Artigo |
|---|---|
| Kieli: | Inglês |
| Julkaistu: |
The Rockefeller University Press
1977
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2180727/ https://ncbi.nlm.nih.gov/pubmed/68993 |
| Tagit: |
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