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Induction of immunological tolerance requires that the B cells can respond to the polyclonal B-cell-activating properties of the thymus- independent antigens

Mice were rendered specifically tolerant to the fluorescein isothiocyanatedextran (FITC) epitope by injection of FITC-dextran B512. Their spleen cells were removed at various times and cultivated in vitro with different polyclonal B-cell activators, such as lipopolysaccharide (LPS), purified protein...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1977
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2180727/
https://ncbi.nlm.nih.gov/pubmed/68993
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