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Mechanochemical analysis of DNA gyrase using rotor bead tracking
DNA gyrase is a molecular machine that uses the energy of ATP hydrolysis to introduce essential negative supercoils into DNA1-3. The directionality of supercoiling is ensured by chiral wrapping of the DNA4,5 around a specialized domain6-9 of the enzyme prior to strand passage. Here we observe the ac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440892/ https://ncbi.nlm.nih.gov/pubmed/16397501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04319 |
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