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mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin
Insulin stimulates protein synthesis by increasing translation initiation. This response is mediated by mTOR and is believed to result from 4EBP1 phosphorylation, which allows eIF4E to bind eIF4G. Here, we present evidence that mTOR interacts directly with eIF3 and that mTOR controls the association...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2006
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440840/ https://ncbi.nlm.nih.gov/pubmed/16541103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601047 |
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