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Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks
The Cdc45 protein is crucial for the initiation of chromosome replication in eukaryotic cells, as it allows the activation of prereplication complexes (pre-RCs) that contain the MCM helicase. This causes the unwinding of origins and the establishment of DNA replication forks. The incorporation of Cd...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440835/ https://ncbi.nlm.nih.gov/pubmed/16601689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601063 |
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