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Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork

Eukaryotic cells regulate the progression and integrity of DNA replication forks to maintain genomic stability and couple DNA synthesis to other processes. The budding yeast proteins Mrc1 and Tof1 associate with the putative MCM–Cdc45 helicase and limit progression of the replisome when nucleotides...

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Detalhes bibliográficos
Main Authors: Calzada, Arturo, Hodgson, Ben, Kanemaki, Masato, Bueno, Avelino, Labib, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1186190/
https://ncbi.nlm.nih.gov/pubmed/16103218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.337205
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