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Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork
Eukaryotic cells regulate the progression and integrity of DNA replication forks to maintain genomic stability and couple DNA synthesis to other processes. The budding yeast proteins Mrc1 and Tof1 associate with the putative MCM–Cdc45 helicase and limit progression of the replisome when nucleotides...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186190/ https://ncbi.nlm.nih.gov/pubmed/16103218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.337205 |
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