Structural Motif-Based Homology Modeling of CYP27A1 and Site-Directed Mutational Analyses Affecting Vitamin D Hydroxylation

Human CYP27A1 is a mitochondrial cytochrome P450, which is principally found in the liver and plays important roles in the biological activation of vitamin D(3) and in the biosynthesis of bile acids. We have applied a systematic analysis of hydrogen bonding patterns in 11 prokaryotic and mammalian C...

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Xehetasun bibliografikoak
Egile Nagusiak: Prosser, David E., Guo, YuDing, Jia, Zongchao, Jones, Glenville
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biophysical Society 2006
Gaiak:
Biophysical Theory and Modeling
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440725/
https://ncbi.nlm.nih.gov/pubmed/16500955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.069369
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