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Identification and characterization of novel sequence variations in the cytochrome P4502D6 (CYP2D6) gene in African Americans

Cytochrome P4502D6 (CYP2D6) genotyping reliably predicts poor metabolizer phenotype in Caucasians, but is less accurate in African Americans. To evaluate discordance we have observed in phenotype to genotype correlation studies, select African American subjects were chosen for complete resequencing...

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Detalhes bibliográficos
Main Authors: Gaedigk, A, Bhathena, A, Ndjountché, L, Pearce, RE, Abdel-Rahman, SM, Alander, SW, Bradford, L DiAnne, Leeder, J Steven
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440720/
https://ncbi.nlm.nih.gov/pubmed/15768052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.tpj.6500305
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