U(S)3 and U(S)3.5 Protein Kinases of Herpes Simplex Virus 1 Differ with Respect to Their Functions in Blocking Apoptosis and in Virion Maturation and Egress

Previously, we reported that the U(S)3 protein kinase blocks apoptosis, that it activates protein kinase A (PKA), that activation of PKA blocks apoptosis in cells infected with a U(S)3 deletion mutant, and that an overlapping transcriptional unit encodes a truncated kinase designated U(S)3.5. Here,...

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Hlavní autoři: Poon, Alice P. W., Benetti, Luca, Roizman, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440442/
https://ncbi.nlm.nih.gov/pubmed/16571792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3752-3764.2006
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