Herpes Simplex Virus Type 1 and 2 Glycoprotein C Prevents Complement-Mediated Neutralization Induced by Natural Immunoglobulin M Antibody

Glycoprotein C (gC) of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) binds complement component C3b and protects virus from complement-mediated neutralization. Differences in complement interacting domains exist between gC of HSV-1 (gC1) and HSV-2 (gC2), since the amino terminus of gC1 bloc...

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Autori principali: Hook, Lauren M., Lubinski, John M., Jiang, Ming, Pangburn, Michael K., Friedman, Harvey M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440426/
https://ncbi.nlm.nih.gov/pubmed/16571820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.4038-4046.2006
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