Partial Delipidation Improves the T-Cell Antigenicity of Hepatitis B Virus Surface Antigen

Hepatitis B virus surface antigen (HBsAg) is a complex macromolecular particle composed of glycoproteins and lipids. The latter, representing 25% of the particle mass, are of host origin and determine the solubility, stability, and, indirectly, B-cell immunogenicity of HBsAg. HBsAg is a T-cell-depen...

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Bibliographische Detailangaben
Hauptverfasser: Desombere, Isabelle, Willems, Annick, Gijbels, Yvonne, Leroux-Roels, Geert
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440404/
https://ncbi.nlm.nih.gov/pubmed/16537618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.7.3506-3514.2006
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