Improvement of Posttranslational Bottlenecks in the Production of Penicillin Amidase in Recombinant Escherichia coli Strains

Using periplasmic penicillin amidase (PA) from Escherichia coli ATCC 11105 as a model recombinant protein, we reviewed the posttranslational bottlenecks in its overexpression and undertook attempts to enhance its production in different recombinant E. coli expression hosts. Intracellular proteolytic...

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Detalles Bibliográficos

Publicado en:	Appl Environ Microbiol
Autores principales:	Ignatova, Z., Mahsunah, A., Georgieva, M., Kasche, V.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Materias:	Enzymology and Protein Engineering
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12571052/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.2.1237-1245.2003
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