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NMR solution structures of LNA (locked nucleic acid) modified quadruplexes

We have determined the NMR solution structures of the quadruplexes formed by d(TGLGLT) and d(TL(4)T), where L denotes LNA (locked nucleic acid) modified G-residues. Both structures are tetrameric, parallel and right-handed and the native global fold of the corresponding DNA quadruplex is retained up...

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Autori principali: Nielsen, Jakob T., Arar, Khalil, Petersen, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435981/
https://ncbi.nlm.nih.gov/pubmed/16614450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl144
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