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Genetic regulators of large-scale transcriptional signatures in cancer

Gene expression signatures encompassing dozens to hundreds of genes have been associated with many important parameters of cancer, but mechanisms of their control are largely unknown. Here we present a method based on genetic linkage that can prospectively identify functional regulators driving larg...

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Detalhes bibliográficos
Main Authors: Adler, Adam S, Lin, Meihong, Horlings, Hugo, Nuyten, Dimitry S A, van de Vijver, Marc J, Chang, Howard Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435790/
https://ncbi.nlm.nih.gov/pubmed/16518402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1752
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