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Genetic regulators of large-scale transcriptional signatures in cancer

Gene expression signatures encompassing dozens to hundreds of genes have been associated with many important parameters of cancer, but mechanisms of their control are largely unknown. Here we present a method based on genetic linkage that can prospectively identify functional regulators driving larg...

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Dettagli Bibliografici
Autori principali: Adler, Adam S, Lin, Meihong, Horlings, Hugo, Nuyten, Dimitry S A, van de Vijver, Marc J, Chang, Howard Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435790/
https://ncbi.nlm.nih.gov/pubmed/16518402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1752
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