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Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics

BACKGROUND: The exchange of nucleotides at synonymous sites in a gene encoding a protein is believed to have little impact on the fitness of a host organism. This should be especially true for synonymous transitions, where a pyrimidine nucleotide is replaced by another pyrimidine, or a purine is rep...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Li, Tang, Chamberlin, Stephen G, Caraco, M Daniel, Liberles, David A, Gaucher, Eric A, Benner, Steven A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435776/
https://ncbi.nlm.nih.gov/pubmed/16545144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-6-25
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