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Renal Phenotype of UT-A Urea Transporter Knockout Mice

The urea transporters UT-A1 and UT-A3 mediate rapid transepithelial urea transport across the inner medullary collecting duct (IMCD). In a previous study, using a new mouse model in which both UT-A1 and UT-A3 were genetically deleted from the IMCD (UT-A1/3(−/−) mice), we investigated the role of the...

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Bibliographic Details
Main Authors: Fenton, Robert A., Flynn, Anneliese, Shodeinde, Adetola, Smith, Craig P., Schnermann, Jurgen, Knepper, Mark A.
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435686/
https://ncbi.nlm.nih.gov/pubmed/15829709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2005010031
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