Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant

Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. Given the role of this gene in viral defense, we sought to explore the poss...

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Main Authors: Urisman, Anatoly, Molinaro, Ross J, Fischer, Nicole, Plummer, Sarah J, Casey, Graham, Klein, Eric A, Malathi, Krishnamurthy, Magi-Galluzzi, Cristina, Tubbs, Raymond R, Ganem, Don, Silverman, Robert H, DeRisi, Joseph L
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2006
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434790/
https://ncbi.nlm.nih.gov/pubmed/16609730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020025
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