Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant

Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. Given the role of this gene in viral defense, we sought to explore the poss...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Urisman, Anatoly, Molinaro, Ross J, Fischer, Nicole, Plummer, Sarah J, Casey, Graham, Klein, Eric A, Malathi, Krishnamurthy, Magi-Galluzzi, Cristina, Tubbs, Raymond R, Ganem, Don, Silverman, Robert H, DeRisi, Joseph L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2006
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434790/
https://ncbi.nlm.nih.gov/pubmed/16609730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0020025
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