Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.

Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. Given the role of this gene in viral defense, we sought to explore the poss...

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Principais autores:	Anatoly Urisman, Ross J Molinaro, Nicole Fischer, Sarah J Plummer, Graham Casey, Eric A Klein, Krishnamurthy Malathi, Cristina Magi-Galluzzi, Raymond R Tubbs, Don Ganem, Robert H Silverman, Joseph L DeRisi
格式:	Artigo
語言:	Inglês
出版:	Public Library of Science (PLoS) 2006-03-01
叢編:	PLoS Pathogens
在線閱讀:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0020025&type=printable
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