Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.

Ribonuclease L (RNase L) is an important effector of the innate antiviral response. Mutations or variants that impair function of RNase L, particularly R462Q, have been proposed as susceptibility factors for prostate cancer. Given the role of this gene in viral defense, we sought to explore the poss...

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Bibliografske podrobnosti

Principais autores:	Anatoly Urisman, Ross J Molinaro, Nicole Fischer, Sarah J Plummer, Graham Casey, Eric A Klein, Krishnamurthy Malathi, Cristina Magi-Galluzzi, Raymond R Tubbs, Don Ganem, Robert H Silverman, Joseph L DeRisi
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2006-03-01
Serija:	PLoS Pathogens
Online dostop:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0020025&type=printable
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