VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-κB signaling pathway

BACKGROUND: Hypoxia-induced mitogenic factor (HIMF) is developmentally regulated and plays an important role in lung pathogenesis. We initially found that HIMF promotes vascular tubule formation in a matrigel plug model. In this study, we investigated the mechanisms which HIMF enhances expression of...

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Hlavní autoři: Tong, Qiangsong, Zheng, Liduan, Lin, Li, Li, Bo, Wang, Danming, Huang, Chuanshu, Li, Dechun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434739/
https://ncbi.nlm.nih.gov/pubmed/16512910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-37
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