Effective Protective Immunity to Yersinia pestis Infection Conferred by DNA Vaccine Coding for Derivatives of the F1 Capsular Antigen

Three plasmids expressing derivatives of the Yersinia pestis capsular F1 antigen were evaluated for their potential as DNA vaccines. These included plasmids expressing the full-length F1, F1 devoid of its putative signal peptide (deF1), and F1 fused to the signal-bearing E3 polypeptide of Semliki Fo...

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Autores principales: Grosfeld, Haim, Cohen, Sara, Bino, Tamar, Flashner, Yehuda, Ber, Raphael, Mamroud, Emanuelle, Kronman, Chanoch, Shafferman, Avigdor, Velan, Baruch
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Microbial Immunity and Vaccines
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC143422/
https://ncbi.nlm.nih.gov/pubmed/12496187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.374-383.2003
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