Age-Related Disparity in Functional Activities of Human Group C Serum Anticapsular Antibodies Elicited by Meningococcal Polysaccharide Vaccine

Serum bactericidal activity confers protection against meningococcal disease, but it is not known whether vaccine-induced anticapsular antibodies that lack bactericidal activity are protective. We developed an infant rat challenge model using a naturally occurring O-acetylated strain of Neisseria me...

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Detalhes bibliográficos
Main Authors: Harris, Shannon L., King, W. James, Ferris, Wendy, Granoff, Dan M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC143411/
https://ncbi.nlm.nih.gov/pubmed/12496177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.275-286.2003
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