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Oral Delivery of Mycobacterium bovis BCG in a Lipid Formulation Induces Resistance to Pulmonary Tuberculosis in Mice

A lipid-based formulation has been developed for oral delivery of Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. The formulated M. bovis BCG was fed to BALB/c mice to test for immune responses and protection against M. bovis infection. The immune responses included antigen-specific cytok...

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Bibliographic Details
Main Authors: Aldwell, Frank E., Tucker, Ian G., de Lisle, Geoffrey W., Buddle, Bryce M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC143408/
https://ncbi.nlm.nih.gov/pubmed/12496154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.101-108.2003
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