Both Family 1 and Family 2 PspA Proteins Can Inhibit Complement Deposition and Confer Virulence to a Capsular Serotype 3 Strain of Streptococcus pneumoniae

Pneumococcal surface protein A (PspA), a virulence factor of Streptococcus pneumoniae, is exceptionally diverse, being classified into two major families which are over 50% divergent by sequence analysis. A family 1 PspA from strain WU2 was previously shown to impede the clearance of pneumococci fro...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Ren, Bing, Szalai, Alexander J., Thomas, Orlanda, Hollingshead, Susan K., Briles, David E.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2003
Assuntos:	Molecular Pathogenesis
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.75-85.2003
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