Both Family 1 and Family 2 PspA Proteins Can Inhibit Complement Deposition and Confer Virulence to a Capsular Serotype 3 Strain of Streptococcus pneumoniae

Pneumococcal surface protein A (PspA), a virulence factor of Streptococcus pneumoniae, is exceptionally diverse, being classified into two major families which are over 50% divergent by sequence analysis. A family 1 PspA from strain WU2 was previously shown to impede the clearance of pneumococci fro...

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Hlavní autoři: Ren, Bing, Szalai, Alexander J., Thomas, Orlanda, Hollingshead, Susan K., Briles, David E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC143380/
https://ncbi.nlm.nih.gov/pubmed/12496151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.75-85.2003
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