Both Family 1 and Family 2 PspA Proteins Can Inhibit Complement Deposition and Confer Virulence to a Capsular Serotype 3 Strain of Streptococcus pneumoniae

Pneumococcal surface protein A (PspA), a virulence factor of Streptococcus pneumoniae, is exceptionally diverse, being classified into two major families which are over 50% divergent by sequence analysis. A family 1 PspA from strain WU2 was previously shown to impede the clearance of pneumococci fro...

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Detaylı Bibliyografya
Yayımlandı:	Infect Immun
Asıl Yazarlar:	Ren, Bing, Szalai, Alexander J., Thomas, Orlanda, Hollingshead, Susan K., Briles, David E.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 2003
Konular:	Molecular Pathogenesis
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC143380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12496151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.1.75-85.2003
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Both Family 1 and Family 2 PspA Proteins Can Inhibit Complement Deposition and Confer Virulence to a Capsular Serotype 3 Strain of Streptococcus pneumoniae

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