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Inhibition of Mycobacterium tuberculosis Glutamine Synthetase as a Novel Antibiotic Strategy against Tuberculosis: Demonstration of Efficacy In Vivo

Tuberculosis remains one of humankind's greatest killers, and new therapeutic strategies are needed to combat the causative agent, Mycobacterium tuberculosis, which is rapidly developing resistance to conventional antibiotics. Using the highly demanding guinea pig model of pulmonary tuberculosi...

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Detalhes bibliográficos
Main Authors: Harth, Günter, Horwitz, Marcus A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC143262/
https://ncbi.nlm.nih.gov/pubmed/12496196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.1.456-464.2003
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