Monolayers of a Model Anesthetic-Binding Membrane Protein: Formation, Characterization, and Halothane-Binding Affinity

hbAP0 is a model membrane protein designed to possess an anesthetic-binding cavity in its hydrophilic domain and a cation channel in its hydrophobic domain. Grazing incidence x-ray diffraction shows that hbAP0 forms four-helix bundles that are vectorially oriented within Langmuir monolayers at the a...

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Detalhes bibliográficos
Main Authors: Churbanova, Inna Y., Tronin, Andrey, Strzalka, Joseph, Gog, Thomas, Kuzmenko, Ivan, Johansson, Jonas S., Blasie, J. Kent
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1432115/
https://ncbi.nlm.nih.gov/pubmed/16473900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072348
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