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Toward the Understanding of MNEI Sweetness from Hydration Map Surfaces

The binding mechanism of sweet proteins to their receptor, a G-protein-coupled receptor, is not supported by direct structural information. In principle, the key groups responsible for biological activity (glucophores) can be localized on a small structural unit (sweet finger) or spread on a larger...

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Détails bibliographiques
Auteurs principaux: De Simone, Alfonso, Spadaccini, Roberta, Temussi, Piero A., Fraternali, Franca
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1432101/
https://ncbi.nlm.nih.gov/pubmed/16461400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.073171
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