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Zinc Protoporphyrin IX Binds Heme Crystals to Inhibit the Process of Crystallization in Plasmodium falciparum

The intraerythrocytic Plasmodium falciparum parasite converts most of host hemoglobin heme into a nontoxic heme crystal. Erythrocyte zinc protoporphyrin IX, normally present at 0.5 μM, which is a ratio of 1:40000 hemes, can elevate 10-fold in some of the anemias associated with malaria disease prote...

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Detalles Bibliográficos
Autores principales: Iyer, Jayasree K, Shi, Lirong, Shankar, Anuraj H, Sullivan, David J
Formato: Artigo
Lenguaje:Inglês
Publicado: ScholarOne 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430826/
https://ncbi.nlm.nih.gov/pubmed/14571325
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