Mouse Polycomb Proteins Bind Differentially to Methylated Histone H3 and RNA and Are Enriched in Facultative Heterochromatin

The chromodomain (CD) of the Drosophila Polycomb protein exhibits preferential binding affinity for histone H3 when trimethylated at lysine 27. Here we have investigated the five mouse Polycomb homologs known as Cbx2, Cbx4, Cbx6, Cbx7, and Cbx8. Despite a high degree of conservation, the Cbx chromod...

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Main Authors: Bernstein, Emily, Duncan, Elizabeth M., Masui, Osamu, Gil, Jesus, Heard, Edith, Allis, C. David
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
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Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430336/
https://ncbi.nlm.nih.gov/pubmed/16537902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.7.2560-2569.2006
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